Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712110 | 0.90 | EPHX1 (0.42) | EPHX1PLA2G2ARXFP1EPHX2 | |
| SCHEMBL6710606 | 0.89 | GRIK1 (0.40) | EPHX1PLA2G2AMEN1KMT2ARXFP1 | |
| SCHEMBL6713177 | 0.88 | NAMPT (0.39) | ROCK2CYP1A2CNR2ALDH1A1HTT | |
| SCHEMBL6710082 | 0.87 | ROCK2 (0.37) | ROCK2RXFP1 | |
| SCHEMBL6708650 | 0.86 | ROCK2 (0.40) | EPHX1TBXA2RROCK2MEN1KMT2A | |
| SCHEMBL6714061 | 0.86 | PLA2G4A (0.39) | PLA2G2ACYP1A2ALDH1A1 | |
| SCHEMBL6707688 | 0.85 | ADORA2B (0.38) | ROCK2CYP1A2ALDH1A1 | |
| SCHEMBL6713409 | 0.84 | TDP2 (0.42) | ROCK2RXFP1 | |
| SCHEMBL6708925 | 0.83 | ADORA2B (0.36) | ROCK2CYP1A2 | |
| SCHEMBL6707687 | 0.83 | PYGM (0.39) | ROCK2MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | EPHX1 1869/4885TBXA2R 457/4885PLA2G2A 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.