SCHEMBL671228

SCHEMBL671228

Nc1ccccc1-c1ccc(C(F)(F)F)cc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
L3MBTL1 Q9Y468 4/20 0.52
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
GAA P10253 2/20 0.50
PKM P14618 1/20 0.50
GPR3 P46089 1/20 0.50
MEN1 O00255 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 2/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
FEN1 P39748 1/20 0.42
CFTR P13569 1/20 0.41
LMNA P02545 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138448 0.89 ALDH1A1 (0.53) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL3784555 0.88 ALDH1A1 (0.52) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL28315996 0.87 HSD11B1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL11415269 0.84 L3MBTL1 (0.46) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL2964383 0.82 ALDH1A1 (0.53) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL398877 0.78 ALDH1A1 (0.58) ALDH1A1L3MBTL1KDM4EHSD17B10TSHR
SCHEMBL398678 0.77 ADORA2A (0.54) ALDH1A1MAPTGAAHSD17B10HPGD
SCHEMBL4521617 0.77 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPTKDM4EGAA
SCHEMBL28607330 0.76 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTKDM4EGAA
Hydrochloric Acid SCHEMBL2846560 0.76 ALDH1A1 (0.56) ALDH1A1L3MBTL1KDM4EHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021606-B2 Multilayer film for electronic circuitry applications E I DU PONT DE NEMOURS AND COMPANY (US) 2021-06-01 US claimed
US-8969909-B2 Light emitting diode assembly and thermal control blanket and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2015-03-03 US claimed
US-8845886-B2 Functionalized filters for heavy oil upgrading EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-09-30 US claimed
US-20130171459-A1 POLYAMIC ACID RESIN SOLUTION CONTAINING INTERPENETRATING POLYMER AND LAMINATE USING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2013-07-04 US claimed
US-20130126940-A1 LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-23 US claimed
US-20120298558-A1 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 US claimed
WO-2012162046-A2 FUNCTIONALIZED FILTERS FOR HEAVY OIL UPGRADING EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-11-29 WO claimed
WO-2012024009-A1 LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-02-23 WO claimed
US-20080138537-A1 Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-06-12 US claimed
EP-1749850-A1 Low color polyimide compositions useful in optical type applications and methods and compositions related thereto E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-02-07 EP claimed
CN-113444366-B Single layer polymer film and electronic device 杜邦电子公司 2025-05-27 CN disclosed
CN-120005240-A Multilayer film, polyimide film and cover film package 杜邦电子公司 2025-05-16 CN disclosed
CN-119920527-A Electrically insulated conductor and method for electrically insulating a conductor 杜邦电子公司 2025-05-02 CN disclosed
CN-119764455-A Current collector and energy storage device 杜邦电子公司 2025-04-04 CN disclosed
CN-119767654-A Cladding layer with polymer film and metal layer 杜邦电子公司 2025-04-04 CN disclosed
EP-0547555-A2 Photocrosslinkable polyimide ammonia salts OCCIDENTAL CHEMICAL CORPORATION (US) 1993-06-23 EP disclosed
US-5209981-A Coatings OCCIDENTAL CHEMICAL CORPORATION (US) 1993-05-11 US disclosed
US-5177181-A Semiconductors OCCIDENTAL CHEMICAL CORPORATION (US) 1993-01-05 US disclosed
EP-0518060-A2 Polyimidesiloxane extended block copolymers OCCIDENTAL CHEMICAL CORPORATION (US) 1992-12-16 EP disclosed
EP-0517002-A2 Diamines and photosensitive polyimides made therefrom OCCIDENTAL CHEMICAL CORPORATION (US) 1992-12-09 EP disclosed