Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KIF11 | P52732 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9251966 | 0.98 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KIF11L3MBTL1JAK2 | |
| Hydrochloric Acid SCHEMBL2846560 | 0.98 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KIF11L3MBTL1JAK2 | |
| SCHEMBL12636456 | 0.88 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KIF11L3MBTL1JAK2 | |
| SCHEMBL17840160 | 0.84 | KIF11 (0.68) | ALDH1A1HSD17B10KIF11JAK2TSHR | |
| SCHEMBL8025255 | 0.82 | KIF11 (0.65) | ALDH1A1HSD17B10KIF11JAK2TSHR | |
| SCHEMBL6480845 | 0.82 | ALDH1A1 (0.83) | ALDH1A1HSD17B10L3MBTL1TSHRKDM4E | |
| SCHEMBL28607330 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KIF11L3MBTL1TSHR | |
| SCHEMBL28930463 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL5647970 | 0.81 | KIF11 (0.47) | ALDH1A1KIF11JAK2TSHRPTGS1 | |
| SCHEMBL4574243 | 0.81 | KIF11 (0.56) | ALDH1A1HSD17B10KIF11JAK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785131-B | Method for synthesizing high-efficiency luminescent complex material with tunable luminescent wavelength | 五邑大学 | 2024-05-17 | — | — | CN | claimed |
| EP-1819223-B1 | USE OF MENADIONE FOR BOOSTING THE EFFECTIVENESS OF AGROCHEMICALS | BASF SE (DE) | 2008-03-12 | — | — | EP | claimed |
| US-11661403-B2 | Oxadiazole compounds | VIVACE THERAPEUTICS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-11186554-B2 | Non-fused tricyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-20210238154-A1 | OXADIAZOLE COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2021-08-05 | — | — | US | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3618818-A1 | NON-FUSED TRICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2020-03-11 | — | — | EP | disclosed |
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
| EP-3216787-B1 | INTERMEDIATES FOR THE PREPARATION OF MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3052495-B1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | PFIZER (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | BASF SE (DE) | 2008-07-31 | — | — | US | disclosed |
| CN-101175727-A | Pyrazole carboxamides as fungicides | BASF AG (DE) | 2008-05-07 | — | — | CN | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
| EP-1881964-A1 | PYRAZOLOCARBOXAMIDES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1856024-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006120219-A1 | PYRAZOLOCARBOXAMIDES AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006092429-A1 | METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS | BASF AKTIENGESELLSCAHFT (DE) | 2006-09-08 | — | — | WO | disclosed |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | VERTEX PHARMACEUTICALS INCORPORATED | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | YAP1, MYC, TEAD2 | ALDH1A1 3497/4885HSD17B10 2588/4885KIF11 2182/4885 |
| US-11186554-B2 | Non-fused tricyclic compounds | YAP1, MYC, TEAD2 | ALDH1A1 3497/4885HSD17B10 2588/4885KIF11 2182/4885 |
| US-20210238154-A1 | OXADIAZOLE COMPOUNDS | YAP1, TEAD2, TEAD3 | ALDH1A1 2353/4885HSD17B10 2502/4885KIF11 2552/4885 |
| US-10662192-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | ALDH1A1 2165/4885HSD17B10 1468/4885KIF11 4684/4885 |
| US-20080183021-A1 | Method for Producing Substituted Biphenyls | CBR3, DDT, HRH3 | ALDH1A1 2309/4885HSD17B10 880/4885KIF11 2708/4885 |
| US-20080071095-A1 | Cystic fibrosis transmembrane conductance | CFTR, ABCB1, ABCC1 | ALDH1A1 2651/4885HSD17B10 1678/4885KIF11 4575/4885 |
| US-20060074075-A1 | including cystic fibrosis transmembrane conductance regulator (\"CFTR\"), used for treating genetic disorders; respiratory system disorders | CFTR, ABCC4, ABCC2 | ALDH1A1 2221/4885HSD17B10 1602/4885KIF11 4443/4885 |
| US-11661403-B2 | Oxadiazole compounds | YAP1, TEAD2, TEAD3 | ALDH1A1 2353/4885HSD17B10 2502/4885KIF11 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.