Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17417711 | 0.91 | PRKAG1 (0.62) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17417668 | 0.84 | PRKAB2 (0.58) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL18088275 | 0.83 | KDM4E (0.54) | CSNK2A2CSNK2BCSNK2A1KDM4EHPGD | |
| SCHEMBL6714522 | 0.82 | HTT (0.51) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL7166839 | 0.82 | GABRA1 (0.63) | KDM4EHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL12786970 | 0.82 | KDM4E (0.52) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL10478126 | 0.82 | KDM4E (0.60) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL5515830 | 0.82 | KDM4E (0.52) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL15054374 | 0.78 | HPGD (0.59) | CSNK2A2CSNK2BCSNK2A1KDM4EHPGD | |
| SCHEMBL5303665 | 0.77 | KDM4E (0.48) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453846-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003042228-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2003-05-22 | — | — | WO | disclosed |