Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553709 | 0.83 | AGTR1 (0.50) | CA1CA2MAPK1TSHRLMNA | |
| SCHEMBL17748601 | 0.81 | GABRA1 (0.57) | CA1CA2MAPK1DRD3SIGMAR1 | |
| SCHEMBL1836066 | 0.78 | CA1 (0.48) | CA1CA2MAPK1TSHRDRD3 | |
| SCHEMBL8068527 | 0.77 | IDO1 (0.53) | MAPK1LMNAAGTR1CYP1A2CYP3A4 | |
| SCHEMBL565137 | 0.76 | HSPA5 (0.50) | CA2MAPK1TSHRCYP3A4KDM4E | |
| SCHEMBL27829507 | 0.75 | DRD3 (0.46) | CA1CA2MAPK1TSHRDRD3 | |
| SCHEMBL300777 | 0.74 | CA1 (0.53) | CA1CA2MAPK1TSHRDRD3 | |
| SCHEMBL28091607 | 0.74 | G6PD (0.36) | TSHRCYP3A4KDM4EALOX15GABRA1 | |
| SCHEMBL7506353 | 0.74 | LMNA (0.59) | CA1CA2LMNAAGTR1CYP1A2 | |
| SCHEMBL7506347 | 0.74 | LMNA (0.59) | CA1CA2LMNAAGTR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325465-A | Biphenyl substituted epithelial sodium channel blocking compounds | 帕里昂科学公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20040013735-A1 | Method for granulation of active substances by low pressure extrusion to obtain directly compressible granules | RHODIA CHIMIE (FR) | 2004-01-22 | — | — | US | disclosed |