Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6707461 | 0.99 | ALDH1A1 (0.42) | RAB9AALDH1A1POLBLMNAFAAH | |
| SCHEMBL6709556 | 0.86 | DRD2 (0.37) | RAB9AALDH1A1TDP1CHRM2CHRM1 | |
| SCHEMBL6712837 | 0.86 | MAPT (0.39) | RAB9AALDH1A1POLBMAPTCCR2 | |
| SCHEMBL6707465 | 0.85 | ALDH1A1 (0.46) | RAB9AALDH1A1POLBTDP1KCNH2 | |
| Hydrochloric Acid SCHEMBL6709619 | 0.85 | DRD2 (0.36) | RAB9AALDH1A1TDP1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6711180 | 0.85 | MAPT (0.38) | RAB9AALDH1A1POLBMAPTCCR2 | |
| Hydrochloric Acid SCHEMBL6709587 | 0.85 | ALDH1A1 (0.45) | RAB9AALDH1A1POLBTDP1KCNH2 | |
| SCHEMBL6707483 | 0.83 | ALDH1A1 (0.45) | RAB9AALDH1A1LMNAMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6713117 | 0.82 | ALDH1A1 (0.44) | RAB9AALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL6712831 | 0.82 | KDM4E (0.48) | RAB9AALDH1A1LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | MERCK PATENT GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | CHRNA1, CHRNA2, CHRNA10 | RAB9A 957/4885ALDH1A1 850/4885POLB 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.