Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6709587 | 0.99 | ALDH1A1 (0.45) | ALDH1A1HSD17B10RAB9ATSHRNPC1 | |
| SCHEMBL6712831 | 0.90 | KDM4E (0.48) | ALDH1A1HSD17B10RAB9ATSHRHPGD | |
| Hydrochloric Acid SCHEMBL6710964 | 0.89 | KDM4E (0.47) | ALDH1A1HSD17B10RAB9ATSHRHPGD | |
| SCHEMBL6712837 | 0.88 | MAPT (0.39) | ALDH1A1HSD17B10RAB9ATSHRNPC1 | |
| SCHEMBL6709556 | 0.88 | DRD2 (0.37) | ALDH1A1HSD17B10RAB9ATSHRNPC1 | |
| Hydrochloric Acid SCHEMBL6709619 | 0.87 | DRD2 (0.36) | ALDH1A1HSD17B10RAB9ATSHRNPC1 | |
| Hydrochloric Acid SCHEMBL6711180 | 0.87 | MAPT (0.38) | ALDH1A1HSD17B10RAB9ATSHRNPC1 | |
| SCHEMBL6707471 | 0.87 | DRD2 (0.38) | TSHRMAPK1KDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6707466 | 0.86 | DRD2 (0.37) | TSHRMAPK1KDM4EDRD2DRD4 | |
| SCHEMBL6713064 | 0.85 | RAB9A (0.42) | ALDH1A1RAB9ATDP1POLBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | MERCK PATENT GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110788-A1 | Nicotinic acetylcholine receptor ligands | CHRNA1, CHRNA2, CHRNA10 | ALDH1A1 850/4885HSD17B10 2389/4885RAB9A 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.