Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710208 | 0.91 | RXFP1 (0.44) | PYGMGRM4GRIK1ROCK1HTR2A | |
| SCHEMBL6714295 | 0.89 | GRIK1 (0.41) | GRM4GRIK1ROCK1RXFP1THRB | |
| SCHEMBL6707687 | 0.89 | PYGM (0.39) | PYGMGRM4ROCK1HTR2ARXFP1 | |
| SCHEMBL6710124 | 0.88 | NPC1 (0.43) | PYGMGRIK1KMT2AMEN1HTT | |
| SCHEMBL6710386 | 0.86 | GRM4 (0.38) | PYGMGRM4ROCK1HTR2ARXFP1 | |
| SCHEMBL6707880 | 0.85 | GAA (0.42) | GRM4GRIK1KMT2AMEN1IMPDH2 | |
| SCHEMBL6709869 | 0.85 | GRIK1 (0.38) | GRM4GRIK1ROCK1KMT2AMEN1 | |
| SCHEMBL6710171 | 0.85 | GRIK1 (0.38) | GRM4GRIK1ROCK1RXFP1THRB | |
| SCHEMBL6713718 | 0.84 | HPGD (0.40) | GRM4GRIK1ROCK1IMPDH2 | |
| SCHEMBL6710123 | 0.84 | ABL1 (0.43) | THRBKMT2AMEN1ABL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PYGM 4115/4885GRM4 4668/4885GRIK1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.