Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709891 | 0.91 | RXFP1 (0.46) | GRIK1BRPF1ROCK1RXFP1ATM | |
| SCHEMBL6714295 | 0.89 | GRIK1 (0.41) | GRIK1ROCK1RXFP1GRM4ALDH1A1 | |
| SCHEMBL6713409 | 0.88 | TDP2 (0.42) | BRPF1ROCK1RXFP1ATMGRM4 | |
| SCHEMBL6710478 | 0.88 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6711838 | 0.86 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6709869 | 0.85 | GRIK1 (0.38) | GRIK1ROCK1GRM4ALDH1A1MEN1 | |
| SCHEMBL6713296 | 0.85 | PYGM (0.40) | GRIK1ROCK1RXFP1GRM4THRB | |
| SCHEMBL6713718 | 0.85 | HPGD (0.40) | GRIK1ROCK1GRM4ALDH1A1 | |
| SCHEMBL6710127 | 0.84 | ROCK1 (0.47) | GRIK1ROCK1RXFP1GRM4MEN1 | |
| SCHEMBL6710124 | 0.84 | NPC1 (0.43) | GRIK1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885BRPF1 95/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.