SCHEMBL6713787

SCHEMBL6713787

CC(=O)c1ccsc1C(C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.37
CYP2C9 P11712 4/20 0.37
ALDH1A1 P00352 4/20 0.37
PTGS1 P23219 4/20 0.37
LMNA P02545 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 2/20 0.37
RXFP1 Q9HBX9 2/20 0.37
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
NR4A1 P22736 1/20 0.36
RECQL P46063 1/20 0.36
ESR2 Q92731 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALOX5 P09917 2/20 0.36
PTK2 Q05397 1/20 0.35
MAPK10 P53779 1/20 0.34
AKR1C3 P42330 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16414458 0.82 ALOX5 (0.39) ALDH1A1PTGS1LMNAKDM4EHPGD
SCHEMBL15344553 0.80 ALDH1A1 (0.54) PTGS2CYP2C9ALDH1A1PTGS1LMNA
SCHEMBL2162247 0.77 ALOX5 (0.53) PTGS2CYP2C9ALDH1A1PTGS1LMNA
SCHEMBL3048188 0.76 ALOX5 (0.40) PTGS2CYP2C9ALDH1A1PTGS1LMNA
SCHEMBL11263884 0.76 PTGS2 (0.38) PTGS2CYP2C9ALDH1A1PTGS1LMNA
SCHEMBL28185456 0.74 AKR1C3 (0.39) PTGS2CYP2C9ALDH1A1PTGS1LMNA
SCHEMBL13129158 0.71 MEN1 (0.47) ALDH1A1LMNAKDM4EHPGDRXFP1
SCHEMBL6918591 0.69 AKR1C3 (0.46) PTGS2CYP2C9ALDH1A1MEN1MAPT
Acetic Acid SCHEMBL11459103 0.68 MEN1 (0.40) ALDH1A1LMNAKDM4EHPGDRXFP1
SCHEMBL3621051 0.68 DHODH (0.51) ALDH1A1LMNAKDM4EHPGDRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040069208-A1 Process for crystallizing enantiomerically enriched 2-acetylthio-3-phenylpropionic acid DSM IP ASSETS B.V. (NL) 2004-04-15 US claimed
EP-1313702-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2003-05-28 EP claimed
WO-2002006217-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2002-01-24 WO claimed
US-20040069208-A1 Process for crystallizing enantiomerically enriched 2-acetylthio-3-phenylpropionic acid DSM IP ASSETS B.V. (NL) 2004-04-15 US disclosed
US-20040069208-A1 Process for crystallizing enantiomerically enriched 2-acetylthio-3-phenylpropionic acid DSM IP ASSETS B.V. (NL) 2004-04-15 US disclosed
EP-1313702-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2003-05-28 EP disclosed
EP-1313702-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2003-05-28 EP disclosed
WO-2002006217-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2002-01-24 WO disclosed
WO-2002006217-A1 PROCESS FOR CRYSTALLIZING ENANTIOMERICALLY ENRICHED 2-ACETYLTHIO-3-PHENYLPROPIONIC ACID DSM N.V. (NL) 2002-01-24 WO disclosed