Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691011 | 0.86 | ALOX5 (0.54) | ALOX5ADRA1DLMNAGSK3BPOLB | |
| SCHEMBL9577306 | 0.85 | ALOX5 (0.50) | ALOX5ADRA1DGSK3BPOLBPKM | |
| SCHEMBL9639925 | 0.82 | ALOX5 (0.51) | ALOX5ADRA1DGSK3BPOLBNPC1 | |
| SCHEMBL3541270 | 0.82 | ALOX5 (0.50) | ALOX5ADRA1DGSK3BPOLBPKM | |
| SCHEMBL7642306 | 0.80 | ALOX5 (0.49) | ALOX5ADRA1DLMNAGSK3BCYP1A2 | |
| Hydrochloric Acid SCHEMBL10919346 | 0.79 | ALOX5 (0.49) | ALOX5ADRA1DLMNAGSK3BCYP2D6 | |
| SCHEMBL11902940 | 0.78 | ALOX5 (0.51) | ALOX5ADRA1DKDM4EGSK3BCYP1A2 | |
| SCHEMBL11263884 | 0.78 | PTGS2 (0.38) | ALOX5CYP2C9PTGS2PTGS1LMNA | |
| SCHEMBL3048188 | 0.78 | ALOX5 (0.40) | ALOX5CYP2C9PTGS2PTGS1LMNA | |
| SCHEMBL6713787 | 0.77 | PTGS2 (0.37) | ALOX5CYP2C9PTGS2PTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139152-A1 | HBV INHIBITOR AND ITS USE | XI'AN XINTONG PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2024-05-02 | — | — | US | disclosed |
| US-11903924-B2 | HBV inhibitor and its use | XI'AN XINTONG PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2024-02-20 | — | — | US | disclosed |
| EP-3919474-B1 | HBV INHIBITOR AND USE THEREOF | XIAN XINTONG PHARMACEUTICAL RES CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |
| EP-4245372-A2 | HBV INHIBITOR AND USE THEREOF | Xi'An Xintong Pharmaceutical Research Co., Ltd. (CN) | 2023-09-20 | — | — | EP | disclosed |
| US-20220184035-A1 | HBV INHIBITOR AND ITS USE | XI'AN XINTONG PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2022-06-16 | — | — | US | disclosed |
| EP-3919474-A1 | HBV INHIBITOR AND USE THEREOF | Xi'An Xintong Pharmaceutical Research Co., Ltd. (CN) | 2021-12-08 | — | — | EP | disclosed |
| WO-2021093172-A1 | HBV INHIBITOR AND USE THEREOF | 西安新通药物研究有限公司 | 2021-05-20 | — | — | WO | disclosed |
| US-8791268-B2 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions | GRUENENTHAL GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8642775-B2 | Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions | GRUENENTHAL GMBH (DE) | 2014-02-04 | — | — | US | disclosed |
| US-20110184020-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20080262039-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2008-10-23 | — | — | US | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
| US-4159986-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | ROUSSEL UCLAF (FR) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11903924-B2 | HBV inhibitor and its use | HAVCR2, HDGF, ZC3HAV1 | ALOX5 4181/4885ADRA1D 4409/4885CYP2C9 902/4885 |
| US-20080262039-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions | TRPV1, TRPV2, TRPV3 | ALOX5 352/4885ADRA1D 341/4885CYP2C9 2152/4885 |
| US-20110184020-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions | TRPV1, TRPV2, TRPV3 | ALOX5 352/4885ADRA1D 341/4885CYP2C9 2152/4885 |
| US-20240139152-A1 | HBV INHIBITOR AND ITS USE | HAVCR2, HDGF, ZC3HAV1 | ALOX5 4181/4885ADRA1D 4409/4885CYP2C9 902/4885 |
| US-20220184035-A1 | HBV INHIBITOR AND ITS USE | HAVCR2, HDGF, ZC3HAV1 | ALOX5 4181/4885ADRA1D 4409/4885CYP2C9 902/4885 |
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | ALOX5 2632/4885ADRA1D 75/4885CYP2C9 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.