Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707932 | 0.98 | GPR35 (0.44) | GPR35ALDH1A1MAPTRXFP1PARP14 | |
| SCHEMBL6710224 | 0.97 | GPR35 (0.46) | GPR35ALDH1A1MAPTRXFP1 | |
| SCHEMBL6709156 | 0.97 | GPR35 (0.40) | GPR35MAPTRXFP1PARP14HIF1A | |
| SCHEMBL6713856 | 0.90 | PLCG2 (0.38) | ALDH1A1PARP14 | |
| SCHEMBL6709868 | 0.90 | GPR35 (0.35) | GPR35MAPTRXFP1HIF1ANPSR1 | |
| SCHEMBL6711624 | 0.89 | HDAC1 (0.35) | GPR35MAPTRXFP1HIF1ANPSR1 | |
| SCHEMBL6711627 | 0.89 | HDAC1 (0.35) | GPR35MAPTRXFP1HIF1ANPSR1 | |
| SCHEMBL6711631 | 0.89 | HDAC1 (0.35) | GPR35MAPTRXFP1HIF1ANPSR1 | |
| SCHEMBL6709998 | 0.88 | GSK3B (0.37) | GPR35ALDH1A1RXFP1PARP14MAP3K5 | |
| SCHEMBL6713465 | 0.88 | GPR35 (0.43) | GPR35RXFP1HIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GPR35 2928/4885ALDH1A1 123/4885AAK1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.