Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25012498 | 0.94 | TSHR (0.61) | TSHRMAPK1MAOAMAP4K4NPC1 | |
| SCHEMBL8741826 | 0.94 | TSHR (0.55) | TSHRMAPK1MAOANPC1MAPT | |
| SCHEMBL27978513 | 0.92 | TSHR (0.59) | TSHRMAPK1MAOAMAP4K4NPC1 | |
| SCHEMBL27978518 | 0.89 | TSHR (0.70) | TSHRMAPK1MAOAMAP4K4NPC1 | |
| SCHEMBL3789224 | 0.88 | TSHR (0.76) | TSHRMAPK1MAOAMAP4K4NPC1 | |
| SCHEMBL3783746 | 0.86 | KIF11 (0.54) | TSHRMAPK1MAOAMAOBKDM1A | |
| SCHEMBL30087058 | 0.86 | KIF11 (0.54) | TSHRMAPK1MAOAMAOBKDM1A | |
| SCHEMBL31729762 | 0.86 | PTPN5 (0.49) | TSHRMAPK1MAP4K4NPC1RAB9A | |
| SCHEMBL5867046 | 0.86 | TSHR (0.47) | TSHRMAPK1MAP4K4NPC1MAPT | |
| SCHEMBL716180 | 0.85 | TSHR (0.50) | TSHRMAPK1MAPTKDM1AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969909-B2 | Light emitting diode assembly and thermal control blanket and methods relating thereto | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-03-03 | — | — | US | claimed |
| US-20130126940-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | claimed |
| WO-2012024009-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | claimed |
| CN-110105572-A | Material used in polyimide precursor, polyimides and its preparation | 宇部兴产株式会社 | 2019-08-09 | — | — | CN | disclosed |
| US-20150361264-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | DU PONT (US) | 2015-12-17 | — | — | US | disclosed |
| US-8969909-B2 | Light emitting diode assembly and thermal control blanket and methods relating thereto | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8853723-B2 | Light emitting diode assembly and thermal control blanket and methods relating thereto | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2597111-A1 | POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME | Ube Industries, Ltd. (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20130126940-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120049220-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012024009-A1 | LIGHT EMITTING DIODE ASSEMBLY AND THERMAL CONTROL BLANKET AND METHODS RELATING THERETO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| US-20090226642-A1 | LOW COLOR POLYIMIDE COMPOSITIONS USEFUL IN OPTICAL TYPE APPLICATIONS AND METHODS AND COMPOSITIONS RELATING THERETO | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-10 | — | — | US | disclosed |
| US-7550194-B2 | Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080138537-A1 | Low color polyimide compositions useful in optical type applications and methods and compositions relating thereto | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2008-06-12 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-1749850-A1 | Low color polyimide compositions useful in optical type applications and methods and compositions related thereto | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-02-07 | — | — | EP | disclosed |
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TSHR 1688/4885MAPK1 4726/4885MAOA 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.