Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713469 | 0.95 | HDAC1 (0.37) | PARP14HDAC3HDAC1MMP2MMP9 | |
| SCHEMBL6710048 | 0.95 | HDAC3 (0.38) | PARP14HDAC3HDAC1MMP2MMP9 | |
| SCHEMBL6711927 | 0.92 | PARP14 (0.44) | PARP14POLB | |
| SCHEMBL6916001 | 0.90 | PARP14 (0.42) | PARP14HDAC3HDAC1POLBHDAC2 | |
| SCHEMBL6711789 | 0.90 | PARP14 (0.36) | PARP14HDAC3HDAC1ALDH1A1POLB | |
| SCHEMBL6707635 | 0.89 | CCKAR (0.38) | PARP14ALDH1A1CCKARCCKBR | |
| SCHEMBL6713713 | 0.89 | ADORA3 (0.37) | PARP14CCKARCCKBRPOLBADORA3 | |
| SCHEMBL6710250 | 0.89 | KMT2A (0.42) | PARP14HDAC1 | |
| SCHEMBL6709996 | 0.88 | GSK3B (0.42) | PARP14HDAC3HDAC1ALDH1A1POLB | |
| SCHEMBL6714114 | 0.88 | ALOX15 (0.45) | HDAC3HDAC1PLCG2HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885HDAC3 2281/4885HDAC1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.