Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229311 | 0.80 | CXCR4 (0.68) | CYP1A2MAOAMAOBSMN1; SMN2CHRM2 | |
| SCHEMBL30487250 | 0.80 | CXCR4 (0.68) | CYP1A2MAOAMAOBSMN1; SMN2CHRM2 | |
| SCHEMBL20859514 | 0.79 | KDM4E (0.73) | MAOAMAOBSMN1; SMN2CHRM2KDM4E | |
| SCHEMBL10405315 | 0.76 | MEN1 (0.61) | CYP1A2SMN1; SMN2CXCR4FABP1FABP6 | |
| SCHEMBL2775016 | 0.76 | CXCR4 (0.47) | CYP1A2SMN1; SMN2CXCR4FABP1FABP6 | |
| SCHEMBL18747185 | 0.76 | MAOA (0.55) | CYP1A2MAOAMAOBSMN1; SMN2CHRM2 | |
| SCHEMBL14824934 | 0.75 | — | — | |
| SCHEMBL230222 | 0.74 | CHRM2 (0.70) | MAOAMAOBSMN1; SMN2CHRM2KDM4E | |
| SCHEMBL29438821 | 0.74 | CHRM2 (0.70) | MAOAMAOBSMN1; SMN2CHRM2KDM4E | |
| SCHEMBL18411909 | 0.74 | MAOA (0.53) | MAOAMAOBSMN1; SMN2CHRM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | claimed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | claimed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | claimed |
| US-20040053977-A1 | Medicinal uses of hydrazones | ALMSTEAD JI-IN KIM (US) | 2004-03-18 | — | — | US | disclosed |
| US-6660737-B2 | Antihypoxic agents | THE PROCTER & GAMBLE COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20030092716-A1 | Medicinal uses of hydrazones | THE PROCTER & GAMBLE COMPANY | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053977-A1 | Medicinal uses of hydrazones | PGF, VEGFA, TEK | CYP1A2 838/4885MAOA 1156/4885MAOB 981/4885 |
| US-20030092716-A1 | Medicinal uses of hydrazones | EPOR, VEGFA, HIF1A | CYP1A2 447/4885MAOA 706/4885MAOB 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.