SCHEMBL6714959

SCHEMBL6714959

CC(C)c1ccc(O[C@@H](C(=O)N2C(=O)OC[C@H]2Cc2ccccc2)[C@@H](O)c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
FAAH O00519 2/20 0.41
HRH3 Q9Y5N1 1/20 0.40
PPARA Q07869 1/20 0.40
BCL2 P10415 1/20 0.40
MDM2 Q00987 1/20 0.40
MCL1 Q07820 1/20 0.40
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
NAAA Q02083 1/20 0.39
NPY5R Q15761 1/20 0.38
ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716171 1.00 L3MBTL1 (0.41) L3MBTL1LMNARXRARXRBMRGPRX4
SCHEMBL6714961 1.00 L3MBTL1 (0.41) L3MBTL1LMNARXRARXRBMRGPRX4
SCHEMBL6718021 1.00 L3MBTL1 (0.41) L3MBTL1LMNARXRARXRBMRGPRX4
SCHEMBL6718013 1.00 L3MBTL1 (0.41) L3MBTL1LMNARXRARXRBMRGPRX4
SCHEMBL6716168 1.00 L3MBTL1 (0.41) L3MBTL1LMNARXRARXRBMRGPRX4
SCHEMBL5609912 0.93 LMNA (0.41) L3MBTL1LMNAFAAHPPARAKMT2A
SCHEMBL5609902 0.93 LMNA (0.41) L3MBTL1LMNAFAAHPPARAKMT2A
SCHEMBL6716423 0.93 GMNN (0.41) LMNAFAAHPPARA
SCHEMBL6713013 0.93 GMNN (0.41) LMNAFAAHPPARA
SCHEMBL6716427 0.93 GMNN (0.41) LMNAFAAHPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040006141-A1 Amidocarboxylic acid compounds SANKYO COMPANY, LTD (JP) 2004-01-08 US disclosed
US-6528525-B1 Amidocarboxylic acid derivatives SANKYO COMPANY, LIMITED (JP) 2003-03-04 US disclosed
EP-1026149-A1 AMIDOCARBOXYLIC ACID DERIVATIVES Sankyo Company Limited (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006141-A1 Amidocarboxylic acid compounds NR1H2, AGK, APOL1 L3MBTL1 1431/4885LMNA 4239/4885RXRA 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.