Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715786 | 0.88 | CCR3 (0.62) | CCR3CHRM2CHRM1BCHEACHE | |
| SCHEMBL6714432 | 0.86 | SLC6A5 (0.57) | CCR3CHRM2CHRM1SSTR5BCHE | |
| SCHEMBL18286595 | 0.81 | SMO (0.54) | CCR3PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL18286601 | 0.81 | SMO (0.53) | CCR3PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL18286588 | 0.81 | SMO (0.53) | CCR3PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL6719419 | 0.80 | CCR3 (0.51) | CCR3CHRM2CHRM1SSTR5DRD4 | |
| SCHEMBL16812619 | 0.80 | SMO (0.48) | CCR3PRKAA2PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL6716204 | 0.79 | CCR3 (0.48) | CCR3CHRM2CHRM1SSTR5DRD4 | |
| SCHEMBL6714169 | 0.79 | CCR3 (0.48) | CCR3CHRM2CHRM1SSTR5DRD4 | |
| SCHEMBL16812616 | 0.79 | PRKAB2 (0.49) | CCR3PRKAA2PRKAB2PRKAG1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034028-A1 | 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors | MERCK PATENT GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| EP-1335912-A1 | 4-(BIPHENYLCARBONYLAMINO)PIPERIDINE DERIVATIVES AS MTP INHIBITORS | MERCK PATENT GmbH (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042291-A1 | 4-(BIPHENYLCARBONYLAMINO)PIPERIDINE DERIVATIVES AS MTP INHIBITORS | MERCK PATENT GMBH (DE) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034028-A1 | 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors | LIPC, CETP, MTTP | CCR3 2275/4885PRKAA2 3558/4885PRKAB2 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.