Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714432 | 0.90 | SLC6A5 (0.57) | CCR3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6715492 | 0.88 | CCR3 (0.56) | CCR3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL3731091 | 0.87 | DRD4 (0.68) | CCR3CHRM2CHRM1CHRM4POLB | |
| SCHEMBL7239441 | 0.86 | CCR3 (0.72) | CCR3POLBSIGMAR1DRD4MEN1 | |
| SCHEMBL13580486 | 0.85 | CCR3 (0.67) | CCR3POLBSIGMAR1DRD4MEN1 | |
| SCHEMBL6719419 | 0.84 | CCR3 (0.51) | CCR3CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL6714325 | 0.84 | MCHR1 (0.57) | CCR3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6716204 | 0.83 | CCR3 (0.48) | CCR3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6714169 | 0.83 | CCR3 (0.48) | CCR3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL6711315 | 0.81 | CCR3 (0.62) | CCR3CHRM2CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034028-A1 | 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors | MERCK PATENT GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034028-A1 | 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors | LIPC, CETP, MTTP | CCR3 2275/4885CHRM2 2977/4885CHRM1 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.