Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL19043110 | 0.94 | THRB (0.47) | THRBTSHRMEN1KMT2AHTT | |
| Di(Hydroxyethyl)Ether SCHEMBL5934631 | 0.92 | THRB (0.45) | THRBTSHRMEN1KMT2AHTT | |
| SCHEMBL2848811 | 0.89 | THRB (0.57) | THRBTSHRMEN1KMT2AHTT | |
| Ethylene Glycol SCHEMBL28082038 | 0.88 | THRB (0.44) | THRBTSHRHTTALDH1A1MAPK1 | |
| Propanol SCHEMBL9222638 | 0.86 | TSHR (0.46) | THRBTSHRALDH1A1MAPK1 | |
| Propanol SCHEMBL9222648 | 0.86 | TSHR (0.46) | THRBTSHRALDH1A1MAPK1 | |
| Propanol SCHEMBL9226264 | 0.86 | TSHR (0.46) | THRBTSHRALDH1A1MAPK1 | |
| Alcohol SCHEMBL9220453 | 0.86 | THRB (0.46) | THRBTSHRHTTALDH1A1MAPK1 | |
| SCHEMBL28149678 | 0.86 | THRB (0.48) | THRBTSHRHTTMAPTALDH1A1 | |
| SCHEMBL23636 | 0.86 | THRB (0.48) | THRBTSHRHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012596-B2 | Photochromic lens substrate | TOKUYAMA CORPORATION (JP) | 2011-09-06 | — | — | US | claimed |
| WO-2024143098-A1 | URETHANE (METH)ACRYLATE, CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENSES, AND EYEGLASSES | 株式会社トクヤマ | 2024-07-04 | — | — | WO | disclosed |
| EP-3995493-B1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORP (JP) | 2024-07-03 | — | — | EP | disclosed |
| CN-114051497-B | Chromene compounds and photochromic optical articles | 株式会社德山 | 2024-06-28 | — | — | CN | disclosed |
| WO-2024128160-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-06-20 | — | — | WO | disclosed |
| WO-2024128158-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-06-20 | — | — | WO | disclosed |
| WO-2024128159-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-06-20 | — | — | WO | disclosed |
| EP-3498742-B1 | PHOTOCHROMIC CURABLE COMPOSITION, USE THEREOF, AND POLYROTAXANE MONOMERS | TOKUYAMA CORP (JP) | 2024-06-12 | — | — | EP | disclosed |
| US-20240182749-A1 | PHOTOCHROMIC CURABLE COMPOSITION, PHOTOCHROMIC LAMINATE AND METHOD FOR PRODUCING THE SAME | TOKUYAMA CORPORATION (JP) | 2024-06-06 | — | — | US | disclosed |
| US-20240158647-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2024-05-16 | — | — | US | disclosed |
| US-6802993-B2 | POLYFUNCTIONAL ACRYLATE MONOMER, A SECOND RADICALLY POLYMERIZABLE MONOMER HAVING A SILANOL GROUP FOR EXCELLENT ADHESION TO A HARD COAT, AND A THIRD MONOMER; HIGH COLOR DENSITY AND FADING SPEED; PLASTIC LENSES | TOKUYAMA CORPORATION (JP) | 2004-10-12 | — | — | US | disclosed |
| US-20040173782-A1 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 2004-09-09 | — | — | US | disclosed |
| EP-1433814-A1 | CURABLE COMPOSITION, CURED ARTICLE OBTAINED THEREFROM, AND PHOTOCHROMIC OPTICAL MATERIAL AND PROCESS FOR PRODUCING THE SAME | Tokuyama Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20040046156-A1 | Photochromic curable composition and cured articles thereof | TOKUYAMA CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| US-6698883-B2 | COLOR DENSITY AND A LARGE FADING RATE, HARDNESS, HEAT RESISTANCE AND SHOCK RESISTANCE; AS OPTICAL MATERIAL SUCH AS A PHOTOCHROMIC LENS MATERIAL | TOKUYAMA CORPORATION (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1359170-A1 | PHOTOCHROMIC CURABLE COMPOSITION AND CURED ARTICLES THEREOF | TOKUYAMA CORPORATION (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-1293522-A1 | CURABLE COMPOSITION COMPRISING PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-1291388-A1 | CURABLE COMPOSITION AND PHOTOCHROMIC CURED ARTICLE | TOKUYAMA CORPORATION (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-20030036579-A1 | Curable composition comprising a photochromic compound | TOKUYAMA CORPORATION (JP) | 2003-02-20 | — | — | US | disclosed |
| US-20030008958-A1 | Curable composition and photochromic cured article | TOKUYAMA CORPORATION (JP) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040173782-A1 | Photochromic composition | CRY1, CRYAA, RB1 | THRB 3917/4885TSHR 3745/4885MEN1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.