Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10700116 | 0.78 | APEX1 (0.38) | KMT2AAPEX1TSHRALDH1A1MEN1 | |
| SCHEMBL443901 | 0.77 | RELA (0.40) | LMNABLMKMT2ANPSR1APEX1 | |
| SCHEMBL6832063 | 0.76 | AKR1B1 (0.45) | KMT2ATSHRHDAC11ALDH1A1MEN1 | |
| SCHEMBL9266535 | 0.76 | ALDH1A1 (0.44) | LMNAKMT2AAPEX1HDAC3TSHR | |
| SCHEMBL1408713 | 0.76 | CYP2C19 (0.40) | LMNABLMTSHRALDH1A1SLC6A6 | |
| SCHEMBL26212048 | 0.75 | ALDH1A1 (0.38) | APEX1GABRPGABRDCYP1A2GABRA1 | |
| SCHEMBL10895115 | 0.75 | RELA (0.49) | KMT2ATSHRHDAC11ALDH1A1MEN1 | |
| SCHEMBL29631557 | 0.74 | LMNA (0.56) | LMNABLMCYP2D6SLC6A6CYP2C19 | |
| SCHEMBL22489397 | 0.73 | CA12 (0.41) | RELACA1CA2CA12CA9 | |
| SCHEMBL26210415 | 0.73 | ECE1 (0.38) | KMT2ANPSR1APEX1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024611-A1 | METHODS OF TREATING SARCOPENIA AND FRAILTY | NATURAL ALTERNATIVES INTERNATIONAL, INC. (US) | 2012-02-23 | — | — | WO | disclosed |
| US-6071545-A | NUTRITIOUS FOOD AND BEVERAGES | VYREX CORPORATION (US) | 2000-06-06 | — | — | US | disclosed |