SCHEMBL6716145

SCHEMBL6716145

CC(C)(C)OC(=O)NCCOc1ccc(CC(NC(=O)OCc2ccccc2)C(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 15/20 0.75
ITGA2B P08514 15/20 0.75
ITGAV P06756 1/20 0.59
MAPT P10636 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PTPN1 P18031 2/20 0.56
SYK P43405 1/20 0.53
ACE P12821 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6716140 1.00 ITGB3 (0.75) ITGB3ITGA2BITGAVMAPTL3MBTL1
SCHEMBL26966055 0.96 ITGB3 (0.72) ITGB3ITGA2BITGAVMAPTL3MBTL1
SCHEMBL27131049 0.96 ITGB3 (0.72) ITGB3ITGA2BITGAVMAPTL3MBTL1
SCHEMBL30149863 0.94 ITGB3 (0.67) ITGB3ITGA2BITGAVMAPTL3MBTL1
SCHEMBL7402776 0.93 ITGB3 (0.72) ITGB3ITGA2BITGAVMAPTPTPN1
SCHEMBL9161400 0.93 ITGB3 (0.72) ITGB3ITGA2BITGAVMAPTPTPN1
SCHEMBL29260893 0.93 ITGB3 (0.66) ITGB3ITGA2BITGAVMAPTL3MBTL1
Potassium Ion SCHEMBL29260880 0.92 ITGB3 (0.64) ITGB3ITGA2BITGAVMAPTL3MBTL1
SCHEMBL30638155 0.89 ITGB3 (0.63) ITGB3ITGA2BMAPTL3MBTL1
SCHEMBL7490606 0.88 ITGB3 (0.64) ITGB3ITGA2BITGAVMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084735-A Photo-delay synthesis method of O- [2- [ [ tert-butyloxycarbonyl ] amino ] ethyl ] -N- [ fluorenylmethoxycarbonyl ] -L-tyrosine 吉尔多肽生物制药(大连市)有限公司 2024-05-28 CN disclosed
US-20040006141-A1 Amidocarboxylic acid compounds SANKYO COMPANY, LTD (JP) 2004-01-08 US disclosed
US-6528525-B1 Amidocarboxylic acid derivatives SANKYO COMPANY, LIMITED (JP) 2003-03-04 US disclosed
EP-1026149-A1 AMIDOCARBOXYLIC ACID DERIVATIVES Sankyo Company Limited (JP) 2000-08-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006141-A1 Amidocarboxylic acid compounds NR1H2, AGK, APOL1 ITGB3 2795/4885ITGA2B 3410/4885ITGAV 3011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.