Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739727 | 1.00 | KDM4E (0.48) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL28058282 | 0.83 | CES2 (0.43) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10316128 | 0.81 | KDM4E (0.53) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12640736 | 0.81 | TDP1 (0.55) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL16416383 | 0.79 | KDM4E (0.46) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20045610 | 0.79 | KDM4E (0.66) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20045612 | 0.79 | CYP3A4 (0.50) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL31538196 | 0.79 | KDM4E (0.46) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL31538137 | 0.79 | KDM4E (0.46) | KDM4ETDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL14207284 | 0.79 | KDM4E (0.55) | KDM4ETDP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973883-B1 | NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BRISTOL MYERS SQUIBB CO (US) | 2012-07-11 | — | — | EP | claimed |
| US-20110021481-A1 | Novel Compounds and Methods for Their Production | BRISTOL-MYERS SQUIBB COMPANY | 2011-01-27 | — | — | US | claimed |
| US-20090253667-A1 | 18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer | BIOTICA TECHNOLOGY LIMITED (GB) | 2009-10-08 | — | — | US | claimed |
| EP-1973883-A2 | NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION | Biotica Technology Limited (GB) | 2008-10-01 | — | — | EP | claimed |
| EP-1928837-A2 | 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER | Biotica Technology Limited (GB) | 2008-06-11 | — | — | EP | claimed |
| WO-2008056188-A2 | NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-05-15 | — | — | WO | claimed |
| WO-2007128829-A2 | 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER | BIOTICA TECHNOLOGY LIMITED (GB) | 2007-11-15 | — | — | WO | claimed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-3964495-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2022-03-09 | — | — | EP | disclosed |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-06-03 | — | — | US | disclosed |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2021-05-04 | — | — | US | disclosed |
| CN-110072842-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2019-07-30 | — | — | CN | disclosed |
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-06 | — | — | US | disclosed |
| WO-2008094438-A1 | MACROLACTAMS BY ENGINEERED BIOSYNTHESIS | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-08-07 | — | — | WO | disclosed |
| US-20080188450-A1 | A 2-azabicyclo(16.3.1)docosa-1(21),4,6,10,18-penntaen-9-ylcarbamate derivative; Heat shock protein 90 inhibitors; hyperproliferative disease, breast cancer, ovarian cancer, leukemia, colon cancer, lung cancer | KOSAN BIOSCIENCES INCORPORATED | 2008-08-07 | — | — | US | disclosed |
| EP-1928837-A2 | 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER | Biotica Technology Limited (GB) | 2008-06-11 | — | — | EP | disclosed |
| WO-2008056189-A1 | 18, 21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008056188-A2 | NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008056188-A2 | NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-05-15 | — | — | WO | disclosed |
| WO-2007128829-A2 | 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER | BIOTICA TECHNOLOGY LIMITED (GB) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166847-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | KDM4E 1646/4885TDP1 738/4885KMT2A 2668/4885 |
| US-10993440-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes related thereto | ACHE, DDT, MLYCD | KDM4E 1646/4885TDP1 738/4885KMT2A 2668/4885 |
| US-20090253667-A1 | 18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer | BCL3, BECN1, CD22 | KDM4E 1367/4885TDP1 2444/4885KMT2A 2175/4885 |
| US-20210161144-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | KDM4E 1609/4885TDP1 683/4885KMT2A 2615/4885 |
| US-20110021481-A1 | Novel Compounds and Methods for Their Production | BCL6, BCL3, AQP4 | KDM4E 2782/4885TDP1 2964/4885KMT2A 3784/4885 |
| US-20080188450-A1 | A 2-azabicyclo(16.3.1)docosa-1(21),4,6,10,18-penntaen-9-ylcarbamate derivative; Heat shock protein 90 inhibitors; hyperproliferative disease, breast cancer, ovarian cancer, leukemia, colon cancer, lung cancer | HSP90AB2P, HSP90AB1, HSPA1B | KDM4E 2715/4885TDP1 3707/4885KMT2A 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.