Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100730 | 0.80 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL6718955 | 0.80 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL4895758 | 0.74 | KDM4E (0.49) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL16547471 | 0.74 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL16547536 | 0.72 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL3149078 | 0.70 | ALKBH2 (0.57) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL6715377 | 0.70 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL2005694 | 0.70 | MAPT (0.45) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL16547541 | 0.70 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AKDM4EMAPT | |
| SCHEMBL15293912 | 0.70 | KDM4E (0.42) | ALDH1A1NPC1RAB9AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102465-A1 | Pyrazolyl pyrimidines | ZYX, P2RX5, P2RX1 | ALDH1A1 1322/4885NPC1 2618/4885RAB9A 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.