Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 5/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723598 | 0.90 | CTSS (0.46) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6719123 | 0.86 | PPARA (0.47) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6724130 | 0.82 | CTSS (0.47) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6724196 | 0.78 | PPARA (0.43) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6722561 | 0.77 | CTSS (0.45) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL22433663 | 0.76 | PPARA (0.57) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL22433357 | 0.76 | PPARA (0.57) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL22433665 | 0.76 | PPARA (0.57) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6723646 | 0.76 | CTSS (0.42) | CTSSPPARAPPARGKLK7KLK5 | |
| SCHEMBL6719065 | 0.75 | PPARA (0.49) | CTSSPPARAPPARGKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |