Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375297 | 1.00 | ALDH1A1 (0.77) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6720375 | 0.89 | MAOB (0.69) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11260728 | 0.88 | ALDH1A1 (0.65) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4130899 | 0.87 | ALDH1A1 (1.00) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL12433977 | 0.87 | CA12 (0.64) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6284605 | 0.84 | NPC1 (0.69) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16541098 | 0.84 | RAB9A (1.00) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL18012070 | 0.83 | NPC1 (0.85) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14158103 | 0.81 | CA12 (0.54) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4792619 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |