Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143595 | 0.85 | CA9 (0.36) | MAPTTDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL1494033 | 0.85 | MAPT (0.38) | MAPTTDP1ALDH1A1KDM4EPOLB | |
| SCHEMBL28331707 | 0.83 | CYP19A1 (0.43) | MAPTTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27942024 | 0.83 | CA2 (0.47) | MAPTTDP1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL25344180 | 0.81 | LMNA (0.36) | ALDH1A1KDM4ECYP1A2L3MBTL1KMT2A | |
| SCHEMBL17924632 | 0.81 | TUBB1 (0.41) | MAPTTDP1ALDH1A1KDM4EL3MBTL1 | |
| Hydrogen Sulfide SCHEMBL28333201 | 0.81 | CYP19A1 (0.42) | MAPTTDP1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL19574045 | 0.81 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL27485684 | 0.81 | IDO1 (0.45) | MAPTTDP1ALDH1A1L3MBTL1POLB | |
| SCHEMBL3674074 | 0.80 | CA9 (0.50) | MAPTTDP1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588854-A | Synthetic method of marine natural product Puupehenol | 哈尔滨工业大学（威海） | 2017-04-26 | — | — | CN | claimed |
| US-6673930-B2 | PREPARING A SELECTIVE GLUCOCORTICOID RECEPTOR AGENTS BY CYCLIZATION, DEHALOGENATION, AMINATION, ETHERIFICATION, HYDROXYLATION | ABBVIE INC. | 2004-01-06 | — | — | US | claimed |
| US-20030069427-A1 | Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro- 1H-chromeno [3,4-f] quinolines and derivatives thereof | ABBVIE INC. | 2003-04-10 | — | — | US | claimed |
| CN-107266410-B | Synthesis method of 8-epi-puupehedione | 威海创惠环保科技有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-107915699-B | Synthetic method of Corallidictyalal D | Weihai Chuang Hui environmental protection & Technology Co., Ltd. (CN) | 2019-12-10 | — | — | CN | disclosed |
| CN-106083803-A | A kind of synthetic method of marine natural products Puupehedione | 哈尔滨工业大学（威海） | 2016-11-09 | — | — | CN | disclosed |
| CN-102391058-B | Method for preparing stilbene compound | UNIV ZHEJIANG TECHNOLOGY | 2013-06-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069427-A1 | Process for the preparation of 5-(substituted)-10 methoxy-2,2,4-trimethyl-2,5-dihydro- 1H-chromeno [3,4-f] quinolines and derivatives thereof | HTR3C, CYP3A5, NQO2 | MAPT 3327/4885TDP1 3280/4885ALDH1A1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.