Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 8/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726098 | 0.92 | PTGS2 (0.42) | PTGS2PTGS1FEN1ALOX5APTOP1 | |
| SCHEMBL6722643 | 0.91 | PTGS2 (0.41) | PTGS2PTGS1FEN1ALOX5APKMO | |
| SCHEMBL6723197 | 0.90 | MALT1 (0.42) | PTGS2PTGS1FEN1ALOX5APMALT1 | |
| SCHEMBL6730013 | 0.90 | PTGS2 (0.43) | PTGS2PTGS1FEN1ALOX5APKMO | |
| SCHEMBL6718600 | 0.90 | GLO1 (0.42) | PTGS2PTGS1FEN1ALOX5APTOP1 | |
| SCHEMBL6723468 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1FEN1ALOX5AP | |
| SCHEMBL6730237 | 0.89 | FEN1 (0.41) | PTGS2PTGS1FEN1ALOX5APMALT1 | |
| SCHEMBL6722680 | 0.89 | PTGS2 (0.39) | PTGS2PTGS1FEN1ALOX5APKMO | |
| SCHEMBL6722946 | 0.88 | TRPV1 (0.43) | PTGS2PTGS1TOP1MALT1 | |
| SCHEMBL6721827 | 0.87 | PDE3B (0.41) | PTGS2PTGS1FEN1ALOX5APKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, PTGES2, FPR1 | PTGS2 5/4885PTGS1 4/4885FEN1 1713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.