Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722787 | 0.88 | KMO (0.43) | KITKMOSIGMAR1TGFBR1MAPK14 | |
| SCHEMBL6722763 | 0.88 | KIT (0.41) | KITKMOSLC34A1SIGMAR1MAPK14 | |
| SCHEMBL6727272 | 0.82 | KIT (0.43) | KITKMOSIGMAR1 | |
| SCHEMBL6719991 | 0.82 | KIT (0.41) | KITKMOSLC34A1SIGMAR1TGFBR1 | |
| SCHEMBL6727232 | 0.77 | AHR (0.40) | — | |
| SCHEMBL6719105 | 0.77 | KCNH2 (0.33) | — | |
| SCHEMBL6722700 | 0.77 | KCNH2 (0.33) | KIT | |
| SCHEMBL6722857 | 0.76 | KIT (0.41) | KITKMOSLC34A1SIGMAR1MAPK14 | |
| SCHEMBL6727171 | 0.75 | TRPA1 (0.43) | KITKMOSLC34A1SIGMAR1 | |
| SCHEMBL6719107 | 0.74 | KCNH2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | KIT 3365/4885KMO 2539/4885SLC34A1 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.