Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026154 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| SCHEMBL6447070 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| Imidacloprid SCHEMBL22278 | 0.84 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| Imidacloprid SCHEMBL12002532 | 0.84 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| Imidacloprid SCHEMBL29436142 | 0.84 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| Imidacloprid SCHEMBL182289 | 0.84 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| Imidacloprid SCHEMBL237917 | 0.84 | ALDH1A1 (0.64) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| SCHEMBL676764 | 0.81 | CHRNA1 (0.66) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| SCHEMBL8113019 | 0.81 | CHRNA1 (0.66) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 | |
| SCHEMBL7638837 | 0.81 | CHRNA1 (0.66) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | WAGNER KLAUS (DE) | 2004-06-24 | — | — | US | disclosed |
| US-6683028-B1 | Cyclic guanidine derivatives and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| EP-1144407-B1 | CYCLIC GUANIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122227-A1 | Cyclic guanidine derivatives and their use as pesticides | PRMT1, GUCY1A1, GUCY1A2 | CHRNB2 527/4885CHRNA4 440/4885ALDH1A1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.