Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.64 |
| ▸ | RXRB | P28702 | 3/20 | 0.64 |
| ▸ | RXRG | P48443 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272450 | 0.86 | RXRA (0.62) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL6725147 | 0.84 | NR4A2 (0.62) | RXRARXRBRXRGNR4A2RAB9A | |
| SCHEMBL8405946 | 0.84 | RXRA (0.50) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL5014148 | 0.83 | RXRA (0.62) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL6723445 | 0.82 | RXRA (0.60) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL1457712 | 0.82 | MEN1 (0.63) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL11349380 | 0.78 | MRGPRX4 (0.68) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL8459965 | 0.77 | RXRA (1.00) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL9813418 | 0.77 | RXRA (1.00) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL16351377 | 0.76 | MRGPRX4 (0.68) | RXRARXRBRXRGNR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |