SCHEMBL672362

SCHEMBL672362

COC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
DGAT1 O75907 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HDAC1 Q13547 4/20 0.36
HDAC7 Q8WUI4 4/20 0.36
HDAC8 Q9BY41 4/20 0.36
HDAC6 Q9UBN7 3/20 0.36
KCNN4 O15554 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517251 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL3082673 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL11205420 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL497763 0.97 DGAT1 (0.39) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL2691635 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL674231 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL516962 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL198030 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL517150 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL497426 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117096453-A Non-combustible electrolyte based on eutectic, preparation method thereof and application thereof in lithium battery 武汉大学 2023-11-21 CN claimed
EP-1337891-B1 SPD FILMS AND LIGHT VALVES COMPRISING SAME RESEARCH FRONTIERS INC (US) 2013-04-03 EP claimed
WO-2012024592-A2 COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-23 WO claimed
US-20240227364-A9 GLAZING WITH ACTIVE AREAS THE CONTROLS OF WHICH ARE IDENTIFIED BY SIGNS PRODUCED USING DIGITAL PRINTING SAINT-GOBAIN SEKURIT FRANCE (FR) 2024-07-11 US disclosed
US-20240131821-A1 GLAZING WITH ACTIVE AREAS THE CONTROLS OF WHICH ARE IDENTIFIED BY SIGNS PRODUCED USING DIGITAL PRINTING SAINT GOBAIN (FR) 2024-04-25 US disclosed
EP-4294771-A1 GLAZING WITH ACTIVE ZONES THE CONTROLS OF WHICH ARE IDENTIFIED BY DIGITALLY PRINTED SIGNS Saint-Gobain Glass France (FR) 2023-12-27 EP disclosed
CN-117096453-A Non-combustible electrolyte based on eutectic, preparation method thereof and application thereof in lithium battery 武汉大学 2023-11-21 CN disclosed
CN-115226398-A Glazing with active area whose control is marked by a marking produced by digital printing 法国圣戈班玻璃厂 2022-10-21 CN disclosed
WO-2022175615-A1 GLAZING WITH ACTIVE ZONES THE CONTROLS OF WHICH ARE IDENTIFIED BY DIGITALLY PRINTED SIGNS SAINT-GOBAIN GLASS FRANCE (FR) 2022-08-25 WO disclosed
WO-2012024592-A2 COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-23 WO disclosed