SCHEMBL3082673

SCHEMBL3082673

COC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
DGAT1 O75907 1/20 0.37
ALDH1A1 P00352 2/20 0.36
HDAC1 Q13547 4/20 0.36
HDAC7 Q8WUI4 4/20 0.36
HDAC8 Q9BY41 4/20 0.36
HDAC6 Q9UBN7 3/20 0.36
KCNN4 O15554 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517251 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL672362 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL11205420 1.00 THRB (0.40) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL497763 0.97 DGAT1 (0.39) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL2691635 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL674231 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL516962 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL198030 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL517150 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7
SCHEMBL497426 0.93 THRB (0.52) THRBDGAT1ALDH1A1HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7794699-B2 compound capable of carrying oxygen comprising dendron, dendrimer, hyperbranched polymer, or dendrigraft having a plurality of branches, each branch including a plurality of repeat units that contain a fluorocarbon moiety and peripheral hydrophilic moieties covalently bonded to terminal repeat units MICHIGAN MOLECULAR INSTITUTE (US) 2010-09-14 US disclosed
US-7358320-B2 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7312298-B2 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY (US) 2007-12-25 US disclosed
US-20060199938-A1 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY 2006-09-07 US disclosed
US-20060199937-A1 Fluorinated reactive compositions for golf balls ACUSHNET COMPANY 2006-09-07 US disclosed
US-20060147414-A1 Nano-structured blood substitutes MICHIGAN MOLECULAR INSTITUTE 2006-07-06 US disclosed
US-6689900-B2 FLUORINATED MULTIFUNCTIONAL ALCOHOL HAVING AT LEAST 3 PRIMARY HYDROXYL GROUPS; ACRYLATED DERIVATIVES THEREOF AS COATINGS FOR FORMING WAVEGUIDE E. I. DU PONT DE NEMOURS AND COMPANY 2004-02-10 US disclosed
US-20020111518-A1 Fluorinated crosslinker and composition ENABLENCE TECHNOLOGIES USA INC. (CA) 2002-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020111518-A1 Fluorinated crosslinker and composition ADH1A, ADH1C, FLNA THRB 3413/4885DGAT1 688/4885ALDH1A1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.