Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6721162 | 0.77 | F2 (0.46) | IDO1F2SLC26A3 | |
| SCHEMBL6725044 | 0.77 | F2 (0.46) | IDO1MAOAMAOBF2RAB9A | |
| SCHEMBL6721262 | 0.76 | IDO1 (0.42) | IDO1MAOAMAOBF2APP | |
| SCHEMBL4265967 | 0.71 | F2 (0.49) | IDO1F2RAB9A | |
| SCHEMBL4276277 | 0.70 | THRA (0.47) | IDO1MAOAMAOBF2CYP1A2 | |
| SCHEMBL4271148 | 0.69 | THRA (0.57) | HIF1A | |
| SCHEMBL6723744 | 0.67 | THRA (0.43) | IDO1F2 | |
| SCHEMBL6731780 | 0.67 | TPMT (0.41) | APP | |
| SCHEMBL6724982 | 0.67 | CXCR1 (0.61) | MAOAMAOBCYP2C19 | |
| SCHEMBL6720850 | 0.67 | TTR (0.50) | APPCYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |