Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.61 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.61 |
| ▸ | CCR4 | P51679 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CHAT | P28329 | 1/20 | 0.46 |
| ▸ | BLVRB | P30043 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TYMS | P04818 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833068 | 0.81 | CXCR1 (0.80) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL6728239 | 0.80 | CXCR1 (0.67) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL19978227 | 0.76 | CXCR1 (0.72) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL19981313 | 0.76 | CXCR1 (0.72) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL6721162 | 0.73 | F2 (0.46) | MEN1KMT2ATHRBLMNAHPGD | |
| SCHEMBL6725044 | 0.73 | F2 (0.46) | RXFP1LMNASMN1; SMN2TP53HPGD | |
| SCHEMBL6721262 | 0.72 | IDO1 (0.42) | L3MBTL1LMNASMN1; SMN2HPGDMAOA | |
| SCHEMBL20999106 | 0.70 | LMNA (0.62) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL16285465 | 0.69 | MAPT (0.73) | CXCR1AVPR2CCR4AKR1C1MEN1 | |
| SCHEMBL20795886 | 0.69 | CFTR (0.61) | CXCR1AVPR2CCR4AKR1C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |