Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.67 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.67 |
| ▸ | CCR4 | P51679 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CHAT | P28329 | 1/20 | 0.55 |
| ▸ | BLVRB | P30043 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833068 | 0.91 | CXCR1 (0.80) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL19978227 | 0.85 | CXCR1 (0.72) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL19981313 | 0.85 | CXCR1 (0.72) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL4957624 | 0.81 | AKR1C1 (0.63) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL6724982 | 0.80 | CXCR1 (0.61) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL18932748 | 0.79 | AKR1C1 (0.68) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL4958920 | 0.76 | LMNA (0.74) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL8142045 | 0.75 | AKR1C1 (0.67) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| SCHEMBL16285465 | 0.74 | MAPT (0.73) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 | |
| Ethane SCHEMBL11224255 | 0.74 | AKR1C1 (0.94) | CXCR1AVPR2CCR4AKR1C1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |