Sugi Predict

Sugi Predict / Compounds / SCHEMBL6725003

SCHEMBL6725003

SCHEMBL6725003

c1ccc(N(c2ccccc2)c2ccc(-c3nc4ccccc4nc3-c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 5/20 0.37
▸ ALDH1A1 P00352 7/20 0.36
▸ LMNA P02545 6/20 0.36
▸ THRB P10828 1/20 0.36
▸ KDM4E B2RXH2 8/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ GAA P10253 3/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ ATM Q13315 1/20 0.35
▸ TLR9 Q9NR96 1/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ MAPT P10636 1/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ RXFP1 Q9HBX9 1/20 0.34
▸ AKT1 P31749 2/20 0.34
▸ HPGD P15428 2/20 0.33
▸ PSMB5 P28074 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12690612 0.94 L3MBTL1 (0.36) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12146785 0.94 L3MBTL1 (0.39) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL6724957 0.94 L3MBTL1 (0.39) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12207326 0.94 L3MBTL1 (0.39) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12146671 0.93 L3MBTL1 (0.40) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL6725649 0.93 ALDH1A1 (0.39) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12146786 0.93 L3MBTL1 (0.38) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12146674 0.92 L3MBTL1 (0.39) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL10315135 0.91 ALDH1A1 (0.36) L3MBTL1ALDH1A1LMNATHRBKDM4E
SCHEMBL12146680 0.91 L3MBTL1 (0.38) L3MBTL1ALDH1A1LMNATHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 — — US disclosed
US-8178216-B2 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-05-15 — — US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 — — US disclosed
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-03-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090072718-A1 Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative CRY1, GRK1, CRY2 L3MBTL1 826/4885ALDH1A1 64/4885LMNA 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.