Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689416 | 0.98 | TSHR (0.38) | TSHRPTAFRKIF11NPC1RAB9A | |
| SCHEMBL21121017 | 0.94 | TSHR (0.35) | TSHRPTAFRKIF11NPC1RAB9A | |
| SCHEMBL28938380 | 0.94 | TSHR (0.35) | TSHRPTAFRKIF11NPC1RAB9A | |
| SCHEMBL28672802 | 0.92 | PTAFR (0.33) | TSHRPTAFRNPC1RAB9ALMNA | |
| SCHEMBL27446803 | 0.86 | KIF11 (0.39) | KIF11NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1241864 | 0.86 | RXRB (0.36) | TSHRPTAFRKIF11NPC1RAB9A | |
| SCHEMBL7624416 | 0.84 | ADORA3 (0.38) | PTAFRNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28860851 | 0.84 | RXRB (0.35) | PTAFRKIF11 | |
| SCHEMBL28198733 | 0.84 | RXRB (0.35) | PTAFRKIF11 | |
| SCHEMBL27687633 | 0.84 | KIF11 (0.38) | KIF11NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445598-B2 | Heterophasic polypropylene with high flowability and excellent low temperature impact properties | BOREALIS TECHNOLOGY OY (FI) | 2013-05-21 | — | — | US | claimed |
| US-8058350-B2 | Polypropylene composition | Basell Poliolefine Italia, s.r.l. (IT) | 2011-11-15 | — | — | US | claimed |
| CN-1249096-C | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2006-04-05 | — | — | CN | claimed |
| CN-1222550-C | Semi-crystalline propylene polymer composition for producing biaxially stretched polypropylene films | BASELL POLYOLEFINE GMBH (DE) | 2005-10-12 | — | — | CN | claimed |
| CN-1433435-A | Transition metal compounds, ligand systems, catalyst systems and their use in the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-07-30 | — | — | CN | claimed |
| CN-1423664-A | Semi-crystalline propylene polymer composition for producing biaxially stretched polypropylene films | BASELL POLYOLEFINE GMBH (DE) | 2003-06-11 | — | — | CN | claimed |
| CN-114599661-B | Transition metal compound, method for preparing the same, and catalyst composition comprising the same | 株式会社LG化学 | 2024-03-12 | — | — | CN | disclosed |
| CN-113508123-B | Transition metal compound and catalyst composition comprising the same | 株式会社LG化学 | 2024-01-16 | — | — | CN | disclosed |
| US-11766669-B2 | Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-09-26 | — | — | US | disclosed |
| CN-113840845-B | Propylene-ethylene random copolymer | 株式会社LG化学 | 2023-08-18 | — | — | CN | disclosed |
| CN-113614124-B | Composite supported metallocene catalyst and method for preparing polyethylene copolymer using the same | 株式会社LG化学 | 2023-06-20 | — | — | CN | disclosed |
| CN-112194749-B | Metallocene catalyst for synthesizing polyolefin elastomer, preparation method and application | 上海葛蓝化工科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-111556878-B | Supported metallocene catalyst and method for preparing polypropylene using the same | LG化学株式会社 | 2023-03-31 | — | — | CN | disclosed |
| WO-2001090112-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001068718-A1 | SALINE CHEMICAL COMPOSITION, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001047635-A2 | SUPPORTED CATALYST SYSTEM CONTAINING A METALLOCENE, A LEWIS BASE AND AN ELEMENTALLY ORGANIC COMPOUND OF MAIN GROUP III AND THE USE THEREOF | BASELL POLYPROPYLEN GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001048034-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001048035-A2 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF AND ITS USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |
| WO-2001040327-A1 | HIGH-MOLECULAR POLYPROPYLENE WITH A BROAD DISTRIBUTION OF THE MOLECULAR WEIGHT AND A SHORT ISOTACTIC SEQUENCE LENGTH | BASELL POLYOLEFINE GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |
| WO-2000020466-A9 | CATALYST SYSTEM | TARGOR GMBH (DE) | 2000-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11766669-B2 | Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof | MLX, ZYX, TXN | TSHR 1812/4885PTAFR 3364/4885KIF11 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.