Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 2/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 14/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397920 | 1.00 | CTSL (0.46) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL757680 | 0.82 | CTSL (0.46) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL6884054 | 0.77 | CTSL (0.47) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL707280 | 0.77 | CTSL (0.47) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL707281 | 0.77 | CTSL (0.47) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL30768091 | 0.72 | CTSL (0.46) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL6856059 | 0.71 | CTSL (0.56) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL30749079 | 0.71 | CTSL (0.56) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL25305712 | 0.70 | ACE (0.41) | LMNA | |
| SCHEMBL13815648 | 0.70 | CTSL (0.48) | CTSLCTSBCTSKCTSHUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022994-A1 | PREPARATION PROCESS OF VILDAGLIPTIN | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2012-02-23 | — | — | WO | disclosed |