Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 16/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884054 | 1.00 | CTSL (0.47) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL707280 | 1.00 | CTSL (0.47) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL30768091 | 0.94 | CTSL (0.46) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL7242696 | 0.87 | — | — | |
| SCHEMBL1303041 | 0.81 | LMNA (0.42) | — | |
| SCHEMBL555100 | 0.81 | LMNA (0.42) | — | |
| SCHEMBL4270704 | 0.81 | LMNA (0.42) | — | |
| SCHEMBL3967423 | 0.79 | ACE (0.40) | — | |
| SCHEMBL757680 | 0.77 | CTSL (0.46) | CTSLCTSBCTSKCTSHUCHL1 | |
| SCHEMBL6856059 | 0.77 | CTSL (0.56) | CTSLCTSBCTSKCTSHUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110592233-B | Gene chip for detecting common food-borne parasites and application thereof | 吉林大学 | 2022-11-08 | — | — | CN | claimed |
| US-20030229226-A1 | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA LTD. (CA) | 2003-12-11 | — | — | US | claimed |
| US-12599684-B2 | Molecular probes and methods of use | CASE WESTERN RESERVE UNIVERSITY (US) | 2026-04-14 | — | — | US | disclosed |
| CN-119104729-A | Glutathione detection reagent and application thereof | 深圳大学 | 2024-12-10 | — | — | CN | disclosed |
| US-20240156995-A1 | MOLECULAR PROBES AND METHODS OF USE | UNIV CASE WESTERN RESERVE (US) | 2024-05-16 | — | — | US | disclosed |
| EP-4259643-A1 | AMATOXIN ANALOGS AND USES THEREOF | The University of British Columbia (CA) | 2023-10-18 | — | — | EP | disclosed |
| US-11738099-B2 | Molecular probes and methods of use | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| CN-116554146-A | FAP-alpha specific radiopharmaceuticals and application thereof | 中国科学院生物物理研究所 | 2023-08-08 | — | — | CN | disclosed |
| WO-2023143502-A1 | FAP-α SPECIFIC RADIOPHARMACEUTICAL AND APPLICATION THEREOF | 中国科学院生物物理研究所 | 2023-08-03 | — | — | WO | disclosed |
| US-11678247-B2 | Method and apparatus to enhance routing protocols in wireless mesh networks | AALBORG UNIVERSITET (DK) | 2023-06-13 | — | — | US | disclosed |
| CN-110592233-B | Gene chip for detecting common food-borne parasites and application thereof | 吉林大学 | 2022-11-08 | — | — | CN | disclosed |
| US-20150353529-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-10 | — | — | US | disclosed |
| US-9156823-B2 | Antiviral compounds | GILEAD PHARMASSET LLC (US) | 2015-10-13 | — | — | US | disclosed |
| US-20140018313-A1 | ANTIVIRAL COMPOUNDS | Gelead Sciences, Inc. | 2014-01-16 | — | — | US | disclosed |
| EP-2640719-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| US-8124584-B2 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090304629-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | MIAO ZHENWEI | 2009-12-10 | — | — | US | disclosed |
| US-7601709-B2 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018313-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | CTSL 868/4885CTSB 630/4885CTSK 1314/4885 |
| US-20240156995-A1 | MOLECULAR PROBES AND METHODS OF USE | EDNRB, FGB, FN1 | CTSL 72/4885CTSB 400/4885CTSK 2182/4885 |
| US-11738099-B2 | Molecular probes and methods of use | DDX21, FUS, DDIT3 | CTSL 3542/4885CTSB 4107/4885CTSK 4257/4885 |
| US-20050153877-A1 | Macrocyclic hepatitis C serine protease inhibitors | PRSS1, SPINT2, TMPRSS4 | CTSL 14/4885CTSB 57/4885CTSK 161/4885 |
| US-20150353529-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | CTSL 868/4885CTSB 630/4885CTSK 1314/4885 |
| US-20030229226-A1 | Cathepsin cysteine protease inhibitors | CTSK, CTSZ, CTSE | CTSL 10/4885CTSB 5/4885CTSK 1/4885 |
| US-20090304629-A1 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, SPINT2, TMPRSS4 | CTSL 15/4885CTSB 56/4885CTSK 152/4885 |
| US-12599684-B2 | Molecular probes and methods of use | TFRC, FGB, SSTR3 | CTSL 306/4885CTSB 449/4885CTSK 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.