SCHEMBL599525

SCHEMBL599525

C/C(=C\C(C)(C)CN)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
GRIK1 P39086 1/20 0.33
PTGS1 P23219 1/20 0.30
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247843 1.00 KDM4E (0.37) KDM4EGRIK1PTGS1AKR1C3
SCHEMBL28154184 0.82 KDM4E (0.32) KDM4E
SCHEMBL6726481 0.82 KDM4E (0.32) KDM4E
SCHEMBL14675185 0.79 PTGS1 (0.31) GRIK1PTGS1AKR1C3
SCHEMBL3621930 0.79 PTGS1 (0.31) GRIK1PTGS1AKR1C3
SCHEMBL1469906 0.79 PTGS1 (0.31) GRIK1PTGS1AKR1C3
SCHEMBL28321184 0.78
SCHEMBL1924255 0.77 PTGS1 (0.30) PTGS1AKR1C3
SCHEMBL1142234 0.77 HMGCR (0.32) PTGS1AKR1C3
SCHEMBL30828310 0.77 HMGCR (0.42) KDM4EPTGS1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11541017-B2 Fortified micronutrient salt formulations MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-01-03 US claimed
US-7819914-B2 Adhesion promoting primer for coated surfaces CORDIS CORPORATION (US) 2010-10-26 US claimed
US-20100152841-A1 ADHESION PROMOTING PRIMER FOR COATED SURFACES CORDIS US CORP 2010-06-17 US claimed
EP-1521574-B1 SOLID PHARMACEUTICAL COMPOSITION CONTAINING A LIPOPHILIC ACTIVE PRINCIPLE AND PREPARATION METHOD THEREOF CLL PHARMA (FR) 2007-03-07 EP claimed
WO-2006110540-A2 ANTIMICROBIAL POLYMER COATINGS AND A METHOD PRODUCING THEM VIA CHEMICAL VAPOUR DEPOSITION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-19 WO claimed
US-20060228966-A1 Chemical vapor deposition of antimicrobial polymer coatings MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-10-12 US claimed
EP-1521574-A1 SOLID PHARMACEUTICAL COMPOSITION CONTAINING A LIPOPHILIC ACTIVE PRINCIPLE AND PREPARATION METHOD THEREOF CLL PHARMA (FR) 2005-04-13 EP claimed
WO-2004000279-A1 SOLID PHARMACEUTICAL COMPOSITION CONTAINING A LIPOPHILIC ACTIVE PRINCIPLE AND PREPARATION METHOD THEREOF CLL PHARMA (FR) 2003-12-31 WO claimed
EP-3891229-B1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED COMMISSARIAT ENERGIE ATOMIQUE (FR) 2024-03-27 EP disclosed
EP-3292866-B1 ACETAMINOPHEN / IBUPROFEN COMBINATIONS JOHNSON & JOHNSON CONSUMER INC (US) 2023-07-26 EP disclosed
US-20220073758-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2022-03-10 US disclosed
EP-3891229-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2021-10-13 EP disclosed
WO-2020115434-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2020-06-11 WO disclosed
US-10363221-B2 Manufacturing solid pharmaceutical dosage forms with visible micro- and nanostructured surfaces and micro- and nanostructured pharmaceutical dosage form I-PROPERTY HOLDING CORP. (US) 2019-07-30 US disclosed
US-5096489-A 2-hydroxyphenyl-s-triazines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5073381-A Sustained drug release UNIVERSITY OF AKRON (US) 1991-12-17 US disclosed
EP-0460385-A2 Polymeric biocidal agents H.B. FULLER LICENSING & FINANCING, INC. (US) 1991-12-11 EP disclosed
EP-0456093-A2 Biguanide derivatives and biocidal compositions containing them H.B. FULLER LICENSING & FINANCING, INC. (US) 1991-11-13 EP disclosed
US-4942204-A METHACRYLOYL ENDCAPPED POLYISOBUTYLENE COPOLYMERIZED WITH DIMETHYLAMINOETHYL METHACRYLATE THE UNIVERSITY OF AKRON (US) 1990-07-17 US disclosed
US-4908381-A Tetrahydropyran containing unsaturated ester or amide derivative ECOLAB INC. (US) 1990-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073758-A1 PROCESS FOR PREPARING A SURFACE WITH BACTERIOSTATIC ACTIVITY AND SURFACE THUS PREPARED DRD1, DRD2, DRD4 KDM4E 4194/4885GRIK1 2299/4885PTGS1 959/4885
US-10363221-B2 Manufacturing solid pharmaceutical dosage forms with visible micro- and nanostructured surfaces and micro- and nanostructured pharmaceutical dosage form MITF, MYOF, RAB5IF KDM4E 3851/4885GRIK1 4526/4885PTGS1 2476/4885
US-11541017-B2 Fortified micronutrient salt formulations SLC5A6, SI, SLC19A1 KDM4E 1929/4885GRIK1 3116/4885PTGS1 439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.