Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036377 | 0.90 | ENPP2 (0.41) | THRBENPP2PTGS1PTGS2AMY1A | |
| SCHEMBL6747956 | 0.88 | ENPP2 (0.36) | THRBENPP2KIF11MAPTTDP1 | |
| SCHEMBL27932425 | 0.88 | ENPP2 (0.36) | THRBENPP2KIF11MAPTTDP1 | |
| SCHEMBL14388835 | 0.85 | AMY1A (0.37) | THRBENPP2PTGS1PTGS2AMY1A | |
| SCHEMBL18813451 | 0.84 | THRB (0.45) | THRBENPP2AMY1ACA2KMT2A | |
| SCHEMBL12589969 | 0.83 | TDP1 (0.48) | THRBPTGS1PTGS2CA2CA12 | |
| SCHEMBL12052514 | 0.83 | TDP1 (0.48) | THRBPTGS1PTGS2CA2CA12 | |
| SCHEMBL18813452 | 0.83 | NT5E (0.34) | THRBENPP2MEN1KMT2ATDP1 | |
| SCHEMBL1937887 | 0.81 | SENP2 (0.47) | THRBENPP2PTGS1PTGS2AMY1A | |
| SCHEMBL1937885 | 0.81 | SENP2 (0.47) | THRBENPP2PTGS1PTGS2AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121527-A1 | BISAZO DYES AND MIXTURES THEREOF | ARCHROMA IP GMBH (CH) | 2017-05-04 | — | — | US | disclosed |
| US-8562694-B2 | Fibre-reactive azo dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120117737-A1 | Fibre-Reactive Azo Dyes, Their Preparation And Their Use | Huntsman Advanced Materials (Switzerland) GNBH (CH) | 2012-05-17 | — | — | US | disclosed |