Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669993 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL30180824 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL669994 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853787 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853799 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL29517213 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL6727788 | 1.00 | AKR1C4 (0.52) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL18853784 | 0.85 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2TBXA2RSLC6A12 | |
| SCHEMBL22814915 | 0.84 | AKR1C4 (0.43) | AKR1C4AKR1C3AKR1C2TBXA2RALDH1A1 | |
| SCHEMBL22814859 | 0.84 | AKR1C4 (0.36) | AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040185075-A1 | Use of at least one (dihydro)jasmonic acid derivative for treating dry skin | L'OREAL S.A. (FR) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040185075-A1 | Use of at least one (dihydro)jasmonic acid derivative for treating dry skin | CUTA, ALOX15, ALOX15B | AKR1C4 1048/4885AKR1C3 890/4885AKR1C2 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.