Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038669 | 0.79 | MAOA (0.35) | — | |
| SCHEMBL6735385 | 0.73 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL3042408 | 0.69 | MAOA (0.45) | SIGMAR1CNR2 | |
| SCHEMBL6086024 | 0.68 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL6733923 | 0.66 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL5764064 | 0.65 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL3045248 | 0.65 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL3045017 | 0.61 | MAOA (0.41) | — | |
| SCHEMBL6726498 | 0.59 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL5765686 | 0.57 | MAPT (0.39) | SIGMAR1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147760-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147760-A1 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | OXA1L, AADAC, MT-ND5 | P2RX7 1463/4885SIGMAR1 1597/4885CNR1 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.