Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514567 | 0.80 | MAPT (0.42) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL439194 | 0.73 | ALDH1A1 (0.41) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL10344433 | 0.73 | CYP1A2 (0.41) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL4429025 | 0.70 | MAPT (0.45) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL16550589 | 0.69 | TSHR (0.43) | CYP1A2CYP2C19CYP2C9PTPN1KCNN4 | |
| SCHEMBL160529 | 0.67 | KCNN4 (0.41) | CYP1A2CYP2C19PTPN1MAPTKMT2A | |
| SCHEMBL7623485 | 0.66 | CYP1A2 (0.46) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL4278139 | 0.66 | CYP1A2 (0.46) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL608329 | 0.66 | ALDH1A1 (0.53) | CYP1A2CYP2C19CYP2C9PTPN1MAPT | |
| SCHEMBL9698748 | 0.65 | CES1 (0.44) | CYP1A2CYP2C19CYP2C9PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067497-B2 | Flame-retardant for engineering thermoplastic applications | BROMINE COMPOUNDS LTD. (IL) | 2011-11-29 | — | — | US | claimed |
| EP-1587865-B1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | BROMINE COMPOUNDS LTD (IL) | 2006-09-13 | — | — | EP | claimed |
| US-20060148948-A1 | Flame-retardant for engineering thermoplastic applications | BROMINE COMPOUNDS LTD. (IL) | 2006-07-06 | — | — | US | claimed |
| JP-2006515035-A | — | — | 2006-05-18 | — | — | JP | claimed |
| EP-1587865-A1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | Bromine Compounds Ltd. (IL) | 2005-10-26 | — | — | EP | claimed |
| WO-2004063263-A1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | BROMINE COMPOUNDS LTD. (IL) | 2004-07-29 | — | — | WO | claimed |
| US-8067497-B2 | Flame-retardant for engineering thermoplastic applications | BROMINE COMPOUNDS LTD. (IL) | 2011-11-29 | — | — | US | disclosed |
| EP-1587865-B1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | BROMINE COMPOUNDS LTD (IL) | 2006-09-13 | — | — | EP | disclosed |
| US-20060148948-A1 | Flame-retardant for engineering thermoplastic applications | BROMINE COMPOUNDS LTD. (IL) | 2006-07-06 | — | — | US | disclosed |
| EP-1587865-A1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | Bromine Compounds Ltd. (IL) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004063263-A1 | FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS | BROMINE COMPOUNDS LTD. (IL) | 2004-07-29 | — | — | WO | disclosed |