Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773229 | 0.87 | PKM (0.60) | PKMALOX15MAPK1KDM4EHTT | |
| SCHEMBL6732655 | 0.84 | SMN1; SMN2 (0.56) | PKMALOX15MAPK1KDM4EHTT | |
| SCHEMBL14359479 | 0.80 | NPC1 (0.55) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL6730228 | 0.79 | NPC1 (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5783680 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL31276466 | 0.77 | NPC1 (0.58) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL28514264 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL17525886 | 0.75 | NPC1 (0.56) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL6734167 | 0.75 | POLB (0.62) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL5495355 | 0.75 | ALDH1A1 (0.68) | GAAALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | EGIS GYOGYSZERGYAR (HU) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | CYP2F1, CYP3A4, CYP2S1 | PKM 291/4885ALOX15 496/4885MAPK1 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.