Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495355 | 0.83 | ALDH1A1 (0.68) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL6729463 | 0.81 | LMNA (0.64) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL24804617 | 0.81 | NPC1 (0.69) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL5783680 | 0.81 | ALDH1A1 (0.57) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL7819650 | 0.80 | NPC1 (0.55) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL6729462 | 0.80 | ALDH1A1 (0.54) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL31276466 | 0.80 | NPC1 (0.58) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL6732655 | 0.80 | SMN1; SMN2 (0.56) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL28440101 | 0.79 | ALDH1A1 (0.73) | POLBALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL28441954 | 0.79 | NPC1 (0.69) | POLBALDH1A1NPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | EGIS GYOGYSZERGYAR (HU) | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | CYP2F1, CYP3A4, CYP2S1 | POLB 1666/4885ALDH1A1 81/4885NPC1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.