SCHEMBL6729025

SCHEMBL6729025

CSc1cccc(SC)c1S(N)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.44
CA1 P00915 9/20 0.44
CA12 O43570 8/20 0.44
CA9 Q16790 6/20 0.44
CA14 Q9ULX7 3/20 0.44
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PTGES2 Q9H7Z7 2/20 0.39
CA7 P43166 5/20 0.36
CA13 Q8N1Q1 4/20 0.36
CA4 P22748 2/20 0.36
CA3 P07451 2/20 0.36
CA6 P23280 2/20 0.36
CA5A P35218 2/20 0.36
CA5B Q9Y2D0 2/20 0.36
PLA2G7 Q13093 1/20 0.36
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819445 0.88 CA2 (0.47) CA2CA1CA12CA9CA14
SCHEMBL3770101 0.86 CA1 (0.39) CA2CA1CA12CA9CA14
SCHEMBL6734275 0.86 PTGES2 (0.46) CA2CA1CA12CA9CA14
SCHEMBL6730193 0.86 KMT2A (0.41) CA2CA1CA12CA9CA14
SCHEMBL6823506 0.82 ALDH1A1 (0.41) CA2CA1CA12CA9CA14
SCHEMBL7029403 0.78 CA2 (0.54) CA2CA1CA12CA9ALDH1A1
SCHEMBL2226182 0.76 CA2 (0.56) CA2CA1CA12CA9CA14
SCHEMBL10582836 0.76 ALDH1A1 (0.39) CA2CA1CA12CA9CA14
SCHEMBL7030801 0.75 TSHR (0.52) CA2CA1CA12CA9CA14
SCHEMBL7030646 0.75 NPC1 (0.46) CA2CA1CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906293-A1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AG (DE) 1999-04-07 EP claimed
WO-1997046540-A1 SUBSTITUTED SULPHONYL AMINO(THIO)CARBONYL COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-11 WO claimed
US-6677277-B1 Substituted sulphonyl amino(thio)carbonyl compounds and their use as herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-01-13 US disclosed
US-4878938-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-07 US disclosed
EP-0135332-B1 HERBICIDAL BENZENESULFONAMIDES, BENZYLSULFONAMIDES AND BENZENESULFAMATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-12-07 EP disclosed
US-4764204-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-16 US disclosed
US-4705556-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-10 US disclosed
US-4604131-A SULFONYLUREA COMPOUNDS; PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-08-05 US disclosed
EP-0135332-A1 Herbicidal benzenesulfonamides, benzylsulfonamides and benzenesulfamates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-03-27 EP disclosed