Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729025 | 0.86 | CA2 (0.44) | CA1CA2CA12CA9CA14 | |
| SCHEMBL9819445 | 0.79 | CA2 (0.47) | CA1CA2CA12CA9CA14 | |
| SCHEMBL6734275 | 0.78 | PTGES2 (0.46) | CA1CA2CA12CA9CA14 | |
| SCHEMBL6730193 | 0.78 | KMT2A (0.41) | CA1CA2CA12CA9CA14 | |
| SCHEMBL13006837 | 0.75 | ALDH1A1 (0.39) | CA1CA2CA12CA9CA14 | |
| SCHEMBL6823506 | 0.74 | ALDH1A1 (0.41) | CA1CA2CA12CA9CA14 | |
| SCHEMBL3776131 | 0.72 | CDK2 (0.44) | CA1CA2CA12CA9CA14 | |
| SCHEMBL3774458 | 0.72 | CA2 (0.45) | CA1CA2CA12CA9CA14 | |
| SCHEMBL3771716 | 0.71 | CA1 (0.43) | CA1CA2CA12CA9PTGES2 | |
| SCHEMBL3772307 | 0.70 | CA2 (0.45) | CA1CA2CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855166-B2 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20100317524-A1 | Sulfonylureas | BAYER CROPSCIENCE AG (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-1877380-A1 | SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| EP-1877386-A1 | HERBICIDALLY ACTIVE PHENYLSULPHONYL-UREA | Bayer CropScience AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-20060264329-A1 | Sulfonylureas | BAYER CROPSCIENCE GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | BAYER CROPSCIENCE GMBH (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1717232-A1 | Phenylsulfonylureas with herbicidal activity | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1717228-A1 | Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators | Bayer CropScience GmbH (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2006114221-A1 | SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2006-11-02 | — | — | WO | disclosed |
| WO-2006114220-A1 | HERBICIDALLY ACTIVE PHENYLSULPHONYL-UREA | BAYER CROPSCIENCE AG (DE) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317524-A1 | Sulfonylureas | IAPP, SLC5A2, SLC5A1 | CA1 1524/4885CA2 418/4885CA12 2065/4885 |
| US-20060258536-A1 | Sulfonylamino(thio)carbonyl compounds | TST, CBR3, MYB | CA1 4582/4885CA2 3775/4885CA12 4407/4885 |
| US-20060264329-A1 | Sulfonylureas | INSR, FFAR3, GPR119 | CA1 2058/4885CA2 1646/4885CA12 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.