Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.47 |
| ▸ | CA1 | P00915 | 11/20 | 0.47 |
| ▸ | CA9 | Q16790 | 9/20 | 0.47 |
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729025 | 0.88 | CA2 (0.44) | CA2CA1CA9CA12CA14 | |
| SCHEMBL2226182 | 0.82 | CA2 (0.56) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9492408 | 0.80 | CA2 (0.55) | CA2CA1CA9CA12CA14 | |
| SCHEMBL3770101 | 0.79 | CA1 (0.39) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6730193 | 0.79 | KMT2A (0.41) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6734275 | 0.79 | PTGES2 (0.46) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6823501 | 0.76 | PTGES2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6823506 | 0.75 | ALDH1A1 (0.41) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1925949 | 0.74 | CA2 (0.45) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7029403 | 0.72 | CA2 (0.54) | CA2CA1CA9CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404758-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| EP-0404758-A4 | HERBICIDAL SULFONAMIDES. | DU PONT (US) | 1989-08-30 | — | — | EP | disclosed |
| US-4854962-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-08 | — | — | US | disclosed |
| US-4746356-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| WO-1987007114-A1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-03 | — | — | WO | disclosed |