Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904861 | 1.00 | LMNA (0.43) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL27713868 | 0.79 | LMNA (0.44) | LMNAMAPK1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7019907 | 0.78 | MAPT (0.45) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL28177269 | 0.78 | CYP1A2 (0.43) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6874329 | 0.78 | MAPT (0.45) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL17093302 | 0.78 | MAPT (0.45) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL16021883 | 0.76 | MAPT (0.47) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL4652167 | 0.76 | PTPN1 (0.43) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6544643 | 0.76 | MAPT (0.47) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL7197406 | 0.76 | MAPT (0.47) | LMNAMAPK1CYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086877-B | A kind of method for splitting of 2 hydracrylic acid class racemoid | 浙江华海药业股份有限公司 | 2017-08-25 | — | — | CN | claimed |
| CN-103086877-A | Splitting method of 2-hydracrylic acid racemic mixture | ZHEJIANG HUAHAI PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-103086877-B | A kind of method for splitting of 2 hydracrylic acid class racemoid | 浙江华海药业股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-103086877-A | Splitting method of 2-hydracrylic acid racemic mixture | ZHEJIANG HUAHAI PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |
| US-6677465-B2 | DIHYDROXYLATION OF 3-PHENYL CINNAMATE BY OSMIUM (VIII) OXIDE CATALYSIS IN PRESENCE OF SHARPLESS LIGAND AND OXIDIZING AGENT, SELECTIVE CONVERSION OF HYDROXY IN 2 POSITION TO LEAVING GROUP, INTRAMOLECULAR SUBSTITUTION TO FORM GLYCIDE ESTER | ABBOTT GMBH & CO. KG (DE) | 2004-01-13 | — | — | US | disclosed |
| US-20030162982-A1 | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters | ROYALTY PHARMA COLLECTION TRUST | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162982-A1 | Method for the enantioselective preparation of 3,3-diphenyl-2,3-epoxy propionic acid esters | ALDH3A1, HAO2, ERGIC1 | LMNA 2262/4885MAPK1 2522/4885CYP1A2 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.